Single dose metrifonate in the treatment of urinary schistosomiasis in an area of low prevalence and intensity of infection
dc.creator | Tswana, S.A. | |
dc.creator | Mason, P.R. | |
dc.date.accessioned | 2016-10-14T07:47:06Z | |
dc.date.accessioned | 2019-05-28T14:36:30Z | |
dc.date.available | 2016-10-14T07:47:06Z | |
dc.date.available | 2019-05-28T14:36:30Z | |
dc.date.created | 2016-10-14T07:47:06Z | |
dc.date.issued | 1986 | |
dc.identifier | Tswana, S. A. & Mason, P. R. (1986). Single dose metrifonate in the treatment of urinary schistosomiasis in an area of low prevalence and intensity of infection. Central African Journal of Medicine, 32 (6),133-137. | |
dc.identifier | 0089176 | |
dc.identifier | http://hdl.handle.net/10646/2836 | |
dc.identifier.uri | http://zdhr.uz.ac.zw/xmlui/handle/123456789/1229 | |
dc.description.abstract | Urine specimens from 638 primary school children in Gokwe Communal Land were examined for S. haematobium ova, and the 187 (29%) children who were excreting eggs were treated with a single lOmg/kg dose of metrifonate. Futher urine samples were collected from all children, whether treated or not, 48 weeks later, and examined for ova. The overall cure rate was 50,8%, and in children not cured egg excretion was reduced by an average 59,9%. Only 12,1% of children were excreting > 50 eggs per ml of urine before treatment, and after this was reduced to 3,9%. Increased egg excretion following treatment was noted in 15 (8,0%) of the infected children, while 21 (4,7%) children with negative urines, and therefore not treated, were excreting eggs 48 weeks later. Thus even in an area where the prevalence and intensity of infection is low, single-dose metrifonate may play a cost-effective role in the control of urinary schistosomiasis. | |
dc.language | en_ZW | |
dc.publisher | University of Zimbabwe, College of Health Sciences | |
dc.subject | Schistosomiasis | |
dc.subject | Urinary Schistosomiasis | |
dc.subject | Helminthiasis | |
dc.subject | Intestinal helminths | |
dc.subject | metrifonate | |
dc.title | Single dose metrifonate in the treatment of urinary schistosomiasis in an area of low prevalence and intensity of infection | |
dc.type | Article |
Files in this item
Files | Size | Format | View |
---|---|---|---|
Tswana_Single_dose_Metrifonate.pdf | 317.0Kb | application/pdf | View/ |