Browsing University of Zimbabwe Theses and Dissertations Collection by Title
Now showing items 56-75 of 306
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Clinical pharmacologist wanted - where?
(University of Zimbabwe, College of Health Sciences, 1999)Many people could define with ease the job of a cardiologist, a paediatrician or an obstetrician. However, only a few would have any clear idea of how a clinical pharmacologist might fill a day. Indeed, within the medical ... -
Co-morbidity of diabetes mellitus and HIV in patients attending the ART clinic Parirenyatwa hospital 2015
(2016-11)Background: Zimbabwe has a double burden of diseases, with HIV epidemic and increased prevalence of diabetes mellitus. Since the roll out of Anti Retroviral Therapy in 2004 at Parirenyatwa OI clinic, Nucleoside Reverse ... -
Comparative evaluation and assessment of the diagnostic usefulness of four commercial HIV-l/HIV-2 antibody assays using two well-characterized serum panels from Blood Transfusion Service and the National Health Laboratory services in Zimbabwe
(University of Zimbabwe, College of Health Sciences, 2001)Objective: To evaluate four Enzyme Linked Immunosorbent Assay ( ELISA) HIV kits for possible use as a combination at the National Health Laboratory Services (NHLS) in Zimbabwe. Design: Laboratory evaluation, sensitivity, ... -
Comparison of CD4+ T-Cell changes in response to highly active antiviral therapy (HAART) in adolescents and children enrolled at Parirenyatwa Hospital Family Care Centre (2005-2010) - Secondary Data Analysis
(2013-08)Background In general, there is an increase in CD4 cell count after initiating on HAART. Despite an increasing trend of access to HAART there is a paucity of studies examining the changes in CD4 count over time in Zimbabwe ... -
Comparison of In Vitro bioavailability of proprietary propranolol preparations
(University of Zimbabwe, College of Health Sciences, 1986-01)Dissolution rate studies were conducted to compare the release rate of propranolol from two proprietary preparations. Propranolol was released at a faster rate from Rexigen* when compared to Inderal* which suggests that ... -
Comparison of retention in care rates among HIV-infected older persons and young adults on higly active antiretroviral therapy at a tertiary hospital in Harare, Zimbabwe
(2016-05)Objective: To evaluate differences in retention in care rates between older individuals and young adults initiated on HAART and to determine the baseline characteristics that are associated with retention in care. Design: ... -
Compliance and loss to follow up of HIV negative and positive mothers recruited from a PMTCT programme in Zimbabwe
(University of Zimbabwe, College of Health Sciences, 2007)Objective: To describe the methodological challenges of a nine months follow up study of mothers recruited from a national Prevention of Mother To Child Transmission (PMTCT) programme with regards to defaulters, drop outs ... -
Congenital duplex gallbladder anomaly presenting as gangrenous perforated intrahepatic cholecystitis mimicking a gas forming liver abscess: A case report and literature review
(University of Zimbabwe, College of Health Sciences, 2012)Background: Ectopic intrahepatic gallbladder is a rare phenomenon. Gallbladder duplication is an even rarer phenomenon. Pathological processes arc more common in congenital anomalies of the gall bladder than normal ... -
Controversies surrounding the use of Parathyroid hormone as a marker of bone metabolism in chronic kidney disease(CKD) patients on haemodialysis in Zimbabwe: The way forward
(2013-09)Background The progressive loss of renal function in chronic kidney disease (CKD) necessitates the eventual use of dialysis. Renal Osteodystrophy (ROD) is a serious complication of CKD with diverse and non-specific ... -
Cryptococcal infection in the era of anti-retroviral therapy (ART) amomg HIV infected patients with meningitis at a tertiary hospital in a low - resource setting.
(2016-05)Background: Despite improved access to anti-retroviral therapy (ART) in Africa, HIV-associated cryptococcal meningitis (CM) appears to remain a cause of substantial morbidity and mortality in sub-Saharan African. This study ... -
Current treatment and future prospects for the management of acute coronary syndromes
(University of Zimbabwe, College of Health Sciences, 1999)The impact of ischaemic heart disease on the burden of cardiovascular disease continues to escalate worldwide. • although international statistics suggest a levelling off in Western world, in the less industrialised parts ... -
Delays in performing emergency caesarean sections at Harare maternity hospital and Mbuya Nehanda hospital: Causes and outcomes
(2017-07)Introduction The ideal decision-to-delivery interval (DDI) for emergency Caesarean sections (ECS) quoted in international guidelines is 30minutes. Achieving this DDI is anticipated to improve perinatal outcomes. It has ... -
Determinants of acute malnutrition in children under five years in Harare City Zimbabwe 2011
(2011-08)Background: Malnutrition is associated with 35% of the top five causes of childhood mortality in Zimbabwe. The aim of the study was to identify factors associated with acute malnutrition in Harare City. Methods: A 1:1 age ... -
Determinants of multidrug resistance amongst turberculosis patients in Matabeleland North and Bulawayo Metropolitan provinces, 2013
(2016-05)Introduction: Multidrug resistance tuberculosis is an emerging threat to the management of TB in Zimbabwe. The aim of the study was to investigate the determinants of MDR-TB in Matabeleland North and Bulawayo Metropolitan ... -
Determinants of Post Natal Care Uptake in Bikita District, Masvingo Province, 2011
(2013-06-10)Postnatal care (PNC) gives an opportunity to detect medical problems of the mother and neonate and reduce morbidity and mortality. In 2010 PNC uptake in Bikita was 43%. This study was conducted to determine factors ... -
Determination of omega-3 long chain polyunsaturated fatty acid levels using dried blood spots in Zimbabwean children aged 7 to 9 years
(2013-06)Background: Blood omega-3 long chain-polyunsaturated fatty acids (LC-PUFAs) have been widely studied in children because of the benefits from optimum physical and mental development. Despite these recognized benefits, the ... -
Determining the rate, nature and predictors of adverse drug reactions associated with the use of Highly Active Antiretroviral Therapy (HAART) in a resource limited setting (Zimbabwe)
(2014-05-23)Background: Dilemmas exist between balancing cost and toxicity of antiretroviral therapy (ART) in resource limited settings (RLS). Most pharmacovigilance programmes in RLS are unable to monitor adverse drug reactions (ADRs) ... -
Development toxicity effects of atorvastatin and rosuvastatin in mice
(2016-05)Background: Statins reduce the risk, morbidity and mortality associated with cardiovascular events, and generally considered safe to use but their safety in pregnancy is not known. Statins are considered potentially ... -
Development, safety and efficacy evaluation of actinic damage retarding nano-pharmaceutical treatments in oculocutaneous albinism
(2017-04)Introduction: There are at least 17 000 Persons living with albinism (PLWA) in Zimbabwe. Oculocutaneous albinism (OCA) is a congenital amelanistic pigmentation disorder that affects all known vertebrates and has no known ... -
Diagnosis of neurological infections in AIDS patients: Possibilities for Zimbabwe
(2000)Routine cerebrospinal fluid (CSF) examination and culture was performed on CSF obtained from 23 HIV infected adults presenting with neurological symptoms at Parirenyatwa Hospital. Bacterial growth was obtained in CSF from ...